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For long-term studies, aliquot into individual portions

In a previous study that matched populations from the Trial to Evaluate Cardiovascular and Other Long-term Outcomes with Semaglutide in Subjects with Type 2 Diabetes (SUSTAIN 6) and Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND) cardiovascular outcome trials using the propensity score method, semaglutide reduced 3-point MACE (cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke) by 26% compared to dulaglutide, although the reduction was not statistically significant (hazard ratio [HR], 0.74

Clean and Pinch Your Thigh Before Administering the Dose Swab the injection site with an alcohol prep pad using a circular motion, starting from the center and working outward

Solvent effects were included using a polarizable continuum model (PCM)

Can I change my injection day if my schedule changes