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Peptic ulcers, severe gastritis, or esophageal varices are common causes
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& Shaw, C
Highlights Sodium-glucose cotransporter-2 inhibitors (SGLT2-i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) provide modest but clinically meaningful blood pressure (BP) lowering effects in people with hypertension and cardiometabolic comorbidities
The following features would enhance the value of an obesity therapeutic, but would likely be assessed in follow-up trials or even post-approval: Additional efficacy in obesity-related co-morbidities
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