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Laxatives may be helpful for some people, but they should be used with care
Across GLP-1 trials, between 26 and 40 percent of total weight lost was lean mass rather than fat
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A 2023 meta-analysis in Nutrients found that protein-rich diets increase postprandial GLP-1 secretion by 20-35%, with sustained effects supporting satiety and metabolic rate
"Triple-hormone-receptor agonist retatrutide for obesityA phase 2 trial." New England Journal of Medicine , 389(6), 514-526
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