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large doses might diminish the effectiveness of antidiabetic medications (like insulin, metformin, or sulfonylureas)
Remove any air bubbles by tapping the syringe and pushing gently on the plunger
U-100 syringe: 100 units = 1 mL
The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]
