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NCT06047548

If the results are confirmed in a larger, phase 3 clinical trial which is expected to run until late 2025 retatrutide could leapfrog another Lilly weight loss drug, tirzepatide, which experts estimated earlier this year could become the best-selling drug of all time

And always avoid any unauthorized megadose vitamin regimens unless your provider approves

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Physical activity amplifies retatrutide results by preserving muscle mass during weight loss (critical for maintaining metabolic rate), increasing the caloric deficit beyond what appetite suppression alone achieves, and improving insulin sensitivity, which supports the metabolic effects of the medication