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Nearly all of KMT2A rearrangements are classified as translocation mutations, which produce a fusion protein that binds to the menin protein, triggering the development of leukemia

The study also noted a decrease in the expression level of pro-atherogenic molecule factors such as plasminogen activator inhibitor-1 (Pai-1) [35]

A previous study from our group did not observe significant changes in CAT activity in the hippocampus and cortex following VPA exposure, reinforcing the variability of antioxidant responses in CNS tissues (Costa et al., 2025)

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