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From there, I spent the next 6 weeks experimenting with a dose of 2mg injected subcutaneously once per week

Activation of glucagon-like peptide-1 receptor in microglia exerts protective effects against sepsis-induced encephalopathy via attenuating endoplasmic reticulum stress-associated inflammation and apoptosis in a mouse model of sepsis

References Office of Dietary Supplements - Carnitine

The UACR ratio also increased by 36.9% (95% CI, 14.1 to 1.1) in the insulin glargine group, but decreased by 6.8% (95% CI, 14.1 to 1.1) in the tirzepatide group

It simply means your body is adjusting to a different chemical signal