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Neither agent is licensed by the MHRA
Determine whether benefits persist during the off period or require continuous use to maintain
Skin feels noticeably firmer to the touch
MECHANISM CATEGORIES SAFETY Side effects GI: nausea, vomiting (titration-dependent) Injection-site reactions Hypoglycemia risk when combined with insulin Known interactions Insulin additive hypoglycemia risk Contraindications History of MTC or MEN2 (theoretical class effect) REGULATORY STATUS FDA Not yet FDA-approved as of 2026-05
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