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These senescent cells release harmful pro-inflammatory signals, known as the senescence-associated secretory phenotype (SASP), that damage surrounding tissues and disrupt overall organ function
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Hill, R
71 Non-proliferative reactive astrogliosis can vary in intensity but is isomorphic such that the astrocytes mainly retain the discrete, non-overlapping cellular domains found in the healthy grey matter but with variable degrees of cellular hypertrophy and reorganisation of their processes
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