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Supplementation may help improve mood and reduce symptoms of depression, particularly in those with B12 deficiency

B12 IV Dose Range The doses for B12 IV therapy range from 500 mcg to 1 mg

Studies show that inhibiting nicotinamide Nmethyltransferase (NNMT) enhances metabolic health by reducing adipose tissue accumulation, improving insulin sensitivity, and promoting better energy utilization

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While losing some lean mass during aggressive weight loss is expected, this ratio is favorable compared to diet-only approaches where lean mass losses can reach 30-40%