Studies have documented higher circulating concentrations of selected POPs after major weight loss, including weight loss following bariatric surgery
One study reported one rat out of 8 expressing human islet amyloid polypeptide (HIP) as a model for diabetes developed pancreatitis when treated with sitaglyptin for 12 weeks (70)
3 Likes Davin8r January 19, 2025, 4:29am #67 nevergiveuphope: They are compounded, and the cost is $349 (+ I think another $100 monthly membership fee), so may be prohibitive for some, but I just found that HenryMeds.com offers PILLS of both Semaglutide AND Tirzepatide, The only people taking these oral versions are unfortunate suckers who dont know any better
Even when approved, many plans impose quantity limits, restrict refills, or require step therapy (trying lower-cost alternatives first), all of which complicate consistent treatment
Aim for half your body weight in ounces of water daily, minimum