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Amylin (also called islet amyloid polypeptide, or IAPP) is a 37-amino-acid peptide hormone co-secreted with insulin from pancreatic beta cells
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Comparative Mechanisms with Other Agents Compared with metformin, which improves insulin sensitivity primarily through hepatic and muscular pathways, GLP-1 RAs act centrally and peripherally to influence appetite, glucose metabolism, and systemic inflammation
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