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The product is usually injected subcutaneously (under the skin) or intramuscularly (into the muscle)

Lyophilized powder is typically favoured in laboratory settings because it allows precise reconstitution, flexible concentration ranges, and greater control over experimental variables

This is likely central to the healing acceleration seen but also raises theoretical concern: chronic pro-angiogenic stimulation in a context of occult malignancy could theoretically be problematic

The typical patient has a soft-tissue injury that stalled: they completed physical therapy, have no surgical indication, but are still symptomatic at 8 to 12 weeks