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Your bones and cartilage get signals from Human Growth Hormone to grow during puberty thus resulting in child growth

Lim J, Lawson GW, Nakamura BN, Ortiz L, Hur JA, Kavanagh TJ, Luderer U

doi: 10.1016/j.mehy.2019.109271

This is a meaningful contrast with recombinant human growth hormone (somatropin), which is exogenous GH given directly

Using data from ClinicalTrials.gov and nationally representative health surveys from the United States (National Health and Nutrition Examination Survey, NHANES) and Korea (Korean National Health and Nutrition Examination Survey, KNHANES), we aimed to characterize the distribution of quantitative eligibility criteria in GLP-1 RA trials registered between 2017 and 2020