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One of the key stumbling blocks at this point was that most of the immunoassays then available relied on antibodies sourced from serum collected from immunised animals or humans, called polyclonal antiserum
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GLP-1R agonists effect(s) on vascular smooth muscle cells are equally important to those on endothelial cells with several favorable responses being reported, including enhanced differentiation, attenuated response to reactive oxygen species, reduced vascular remodeling through improved mitochondrial activity and dynamics, and the prevention of aberrant migration [65]
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