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They help with muscle growth, tissue repair, enzyme production, and hormone regulation

This creates an elevated TIMP:MMP ratio that correlates with collagen and elastin synthesis stimulation

doi:10.7554/eLife.02200 Kenzelmann Broz D, Spano Mello S, Bieging KT et al (2013) Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses