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The combination approach appears most promising for long-term sustainability
At year 5: the drug would be two to three times more expensive than surgery 4
These medications excel at glycemic control and produce substantial weight loss through mechanisms centered on insulin secretion enhancement, glucagon suppression, and central appetite regulation via GLP-1 pathways
Taking them simultaneously ensures this synergistic cycle can begin immediately upon absorption
M., Ossendorff, R., Gilat, R
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