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Sakurai T (2007) The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness

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reported that HTY may interfere with GPER-mediated estrogen receptor rapid signaling in MCF7 cells, and HTY exposure was associated with inhibition of estrogen-dependent ERK1/2 signaling [86]

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7 Clinical studies on breast cancer using natural supplements In a study, subgroups of breast cancer were evaluated those without mammary abnormalities in the extra tumour epithelium glandular, those with non-proliferative breast cancer (n=127) and finally, 155 NPFCs and 185 PFCs were compared with their respective controls (n=903 vs 127 normal) (240)