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In fact, the use of GSTP1 knockout mice demonstrated that loss of GSTP1 expression increases sensitivity to metabolic or environmental toxins and promotes mutations and cancer development ( FIGURE 2 Prostate cancer Promoter hypermethylation leading to epigenetic silencing of GSTP1 gene expression is frequently detected in prostate cancer cells, the most commonly diagnosed type of malignancy among men in Western European countries and the second cause of cancer-related deaths among men worldwide ( Figure 2 )
For others, results appear gradually as part of consistent wellness habits
This central action provides a strong basis for its role in neuroprotection against biochemical insults and stress
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Normal epithelial and fibroblast cells treated with Epithalon concentrations ranging from 0.1 to 1 g/ml demonstrated significant telomere elongation through hTERT mRNA upregulation and telomerase enzyme activation
