A recent study investigated the effects of GLP-1R agonists in a multi-hit mouse model in which the combination of a high-fat diet and angiotensin II-induced a cardiometabolic HFpEF phenotype that resembles the human HFpEF phenotype to a large extent characterized by obesity, impaired glucose handling, and metabolic dysregulation accompanied by inflammation
Dont smoke
Thyroid Medication and GLP-1 Therapy If youre on thyroid medications such as levothyroxine, liothyronine, or desiccated thyroid extract, weight loss from GLP-1 therapy could increase your risk of hyperthyroidism
Opiates Exendin-4 and liraglutide reduced cue- and drug-induced opiate-seeking behavior in rats and mice across several studies 83,84,85,86,87,88
Ozempic, Wegovy, Mounjaro, and Zepbound are prescription medications, and their side effects should be managed with the licensed provider who prescribes and supervises your treatment