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Incretin Hormones in Obesity and Related Cardiometabolic Disorders: The Clinical Perspective

Korsten M, Matsuzaki S, Feinman L, Lieber C

First, let's review some of the basics of GLP-1

Metformin should not be used by anyone who: Is pregnant or breastfeeding Has poor kidney or liver function Has hypoxia (low oxygen levels) Has acute or chronic metabolic acidosis, with or without coma Alternatives to Ozempic and metformin If you cannot take Ozempic, metformin, or both, there are alternatives for treating type 2 diabetes or losing weight that might be worth considering

The Medicines and Healthcare products Regulatory Agency (MHRA) approved Ozempic for use alongside diet and exercise modifications, either as monotherapy when metformin is inappropriate or in combination with other glucose-lowering medications