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Policy Diabetes mellitus (DM) is a global health concern, affecting approximately 10.5% of adults worldwide, with projections indicating an increase to over 12% by 2045, notes study author Samita Garg, MD, Department of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic

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The uncontrolled generation of GSSG during oxidative stress can contribute to mitochondrial dysfunction by glutathionylation of target proteins, as described below