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For uterine fibroids, most therapeutics focus on two symptoms, bleeding management and shrinking fibroid size, which translates to a smaller pipeline
Specifically, GLP-1RAs exert protective effects on exercise-induced cardiomyopathy via increasing autophagy, reducing inflammation-related proteins and ROS generation via restoring the expression of catalase and manganese superoxide dismutase (MnSOD) [81]
For significant wounds, combined use under clinical direction makes sense
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Mandavilli BS, Santos JH, Van Houten B: Mitochondrial DNA repair and aging
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