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In parallel, data from the SELECT trial involving semaglutide revealed a notable decrease in recurrent cardiovascular risks among overweight or obese individuals who had undergone bypass surgery, signaling its promise as a secondary prevention therapy

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For example, alcohol affects the digestive system, which is a common concern for people who take GLP-1s

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On the other hand, a trial verdict, while less secure, can be disputed and overturned on appeal

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Can this happen again to other shortage drugs

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Cardiovascular outcomes, long-term efficacy and safety In people with T2D and established cardiovascular disease, the international guidelines for T2D recommend the use of GLP-1 RA or sodium glucose co-transporters 2 inhibitors (SGLT-2i) as first-line treatment (independent of HbA1c), based on multiple trials demonstrating their cardio-renal benefits [109]

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