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Similar to our previous RNA-seq analysis, we demonstrate that treatment with GLP-1MK-801 significantly regulates around 150 times the number of hypothalamic transcripts relative to the weight-matched semaglutide-treated group, emphasizing a mode of action for GLP-1MK-801 that involves biological pathways independent of the GLP-1 receptor signalling pathway (Fig
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doi: 10.1016/j.diabres.2008.09.037 49 KendallDMRiddleMCRosenstockJZhuangDKimDDFinemanMSet al
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