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In a clinical trial for weight reduction that included an intensive lifestyle intervention lead-in period (Study 3), 287 patients were treated with ZEPBOUND for up to 72 weeks

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It is known that peptide 20 potently reversed metabolic disorders in rodent models of obesity and diabetes, characteristic of increased energy expenditure and elevated circulating FGF21 levels as a result of GCGR agonism 22,23

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