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Severe nausea and vomiting may lead to esophageal irritation, gastroesophageal reflux, or musculoskeletal strain from retchingall of which can manifest as chest discomfort

Those products come in pre-filled pens with dose selectors calibrated in milligrams

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Jill Furman, FDLI Enforcement Conference (December 2025)

6 An enzyme called DPP-4 circulates in the blood and cleaves the peptide almost immediately after it is released, cutting between the second and third amino acids and rendering it biologically inactive