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Researchers evaluated participants enrolled in the ongoing CU Anschutz-led RESTORE clinical trial, which is investigating the role of semaglutide in restoring ovulation and improving reproductive health in adolescents and adults with PMOS

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Unlike broad anti-inflammatory drugs, senolytics work by exploiting the unique survival dependencies of senescent cells, targeting pro-survival pathways such as BCL-2/BCL-xL, PI3K/AKT, and HSP90 that senescent cells upregulate to resist apoptosis

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Glutathione: subcellular distribution and membrane transport (1)