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A prior upper respiratory or gastrointestinal viral infection will lead to reduced oral intake in these infants which can precipitate the acute crisis
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The relevance to humans remains uncertain, as human thyroid C-cells express far fewer GLP-1 receptors than rodent C-cells
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157,159 Interestingly, another receptor, S1PR2, which is found in peritoneal macrophages in mice, is more effective at inhibiting the LPS-induced inflammatory response
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Front Immunol 2022;13:784046
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