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In addition, compared with placebo, carnitine administration in women with PCOS led to a significant reduction in fasting plasma glucose (038 036 vs +011 097 mmol/l, P = 001), serum insulin levels (1439 2580 vs +301 3725 pmol/l, P = 004), homoeostasis model of assessment-insulin resistance (061 103 vs +011 143, P = 004) and dehydroepiandrosterone sulphate (364 700 vs 059 320 mol/l, P = 003)
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To determine the specific acyl-carnitine species that were consistently elevated across the subgroup of patients with consistently abnormal acyl-carnitine panels, we examined the first two acyl-carnitine panels measured for each patient
It was reported that it could raise intracellular GSH by increasing SLC7A11 expression, efficiently leading to GPX4 enhancement and ferroptosis suppression in the ISO-induced injury model of H9C2 cells and rat myocardium [49]
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