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Model: Female US NIH National Institute on Aging (NIA) Aged Rodent Colony mice aged 22 months Dosage: 10 mg/kg of 5-amino-1MQ administered with subcutaneous injections for eight weeks
We watch for signs like less fatigue, better nerve function, and overall health
BAC Between 0.05% to 0.08%: Moderate impairment, affecting coordination and judgment
A 29 or 30 gauge needle minimizes discomfort during injection
These murine models were initially presented with corticosteroids, which reportedly contributed to severe muscular damage in these murine models
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