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The strongest published finding is from the foundational Biochemical Pharmacology study by Neelakantan et al.: in diet-induced obese mice, daily 5-Amino-1MQ administration produced reductions in body weight, white adipose tissue mass, and adipocyte size without any significant change in food intake

The causes of this deficiency include poor dietary intake, malabsorption, and pernicious anemia

Other contraindications and caution flags include Wilsons disease or another copper-handling disorder, pregnancy, recent surgery, and WADA-tested competition

While some formulations are designed to enhance oral absorption, they don't always fully overcome these inherent biological hurdles

Thousands of Americans are taking it