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A 2025 systematic review and meta-analysis in Obesity Reviews found that significant weight is regained after GLP-1 receptor agonist treatment is discontinued, which supports the need for continuity planning before therapy ends [5]
Similar effects were seen with liraglutide, the active ingredient in the weight loss drug Saxenda, and the diabetes drug Victoza
Do injections work better than tablets
Patients should understand that while the medication itself won't show up on blood tests, the therapeutic effects of GLP-1 drugs are clearly evident through improved metabolic markers: lower HbA1c, reduced fasting glucose, potential improvements in lipid profiles, and weight loss
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