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Even so, prior studies suggest that up to 65 % of patients discontinue them within a year, and discontinuation has been associated with weight regain and reduced cardiometabolic benefits
This is a good idea, even if you arent on weight loss medications, particularly for post-menopausal women
It has also been shown to protect against heart attacks, strokes, and death in people with diabetes
Paradoxically, this means the very people who benefit most from semaglutide weight loss are also most likely to experience reflux, at least initially
Use of GLP-1RA is protective and prevents bone fractures over a longer period of use in T2DM patients in a recent trial in 2020 liraglutide showed to have decreased bone resorption compared to placebo (120)
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