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Typically, application of one 1mg dose once weekly constitutes the intermediate therapeutic dose for the restoration of physiological equilibrium during the escalation phase

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Levothyroxine absorption can be significantly reduced by certain supplements and medicines , including: Calcium and iron supplements Bile acid sequestrants (cholestyramine, colesevelam) Orlistat Aluminium- or magnesium-containing antacids Sucralfate Sevelamer Maintain at least a 4-hour interval (or longer for bile acid sequestrants) between taking levothyroxine and these agents