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Hence, the effects of GLP-1 RA on the central nervous system may contribute to the induction of weight loss but not necessarily to its maintenance

An exploratory mediation analysis of stroke outcomes in the REWIND CVOT, in which dulaglutide reduced systolic blood pressure (SBP) by a mean of 1.7 mmHg compared to placebo, found that the blood pressure reduction caused by dulaglutide accounts for around 14% of its effect on stroke risk [21]

This is why many people explore ways to boost glutathione levels, either naturally or through supplementation

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