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Glucagon-like peptide-1 (GLP-1) is an extensively well-characterized incretin hormone which regulates both insulin and glucagon secretion
Further tests on obese rats supported the idea that tesofensine could reduce body weight, so NeuroSearch decided to focus on developing it as an oral anti-obesity drug
This applies to every standard test your primary care doctor, endocrinologist, or clinic might order
Study monitoring Independent oversight committees included the Data Monitoring Committee (DMC), the Trial Steering Committee (TSC) and the Trial Management Committee, and were held on a regular basis throughout the trial
An elevated resting heart rate can increase long-term cardiovascular risk, and regulators need robust data confirming that the metabolic benefits outweigh this potential downside
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