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At L5-S1, the S1 nerve root compression follows a different path, running from the lower back or buttock down the back of the thigh into the calf and heel

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Although there is a dearth of bioavailability data for many of the peptide nasal sprays, a study showed that direct intratracheal instillation of a lyophilized powder at high concentrations could achieve reasonable levels of systemic absorption [13]

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