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Lifestyle Factors: Lack of physical activity and obesity are closely linked to high triglycerides
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Based on this research, it appears a significant proportion of metformins action could be attributed to its effect on the lower digestive tract (Buse 2016)
Zepbound should be discontinued if pregnancy is confirmed
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The combination yields greater weight loss than either agent alone, with mean reductions in body weight of approximately 20.4% over 68 weeks in non-diabetic adults and 13.7% in those with type 2 diabetesfar exceeding placebo and monotherapy arms
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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