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For context, these figures are notably higher than those reported in placebo-controlled trials of currently approved agents such as semaglutide 2.4 mg (Wegovy) and tirzepatide (Mounjaro)

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This is the first interventional Alzheimers drug trial focused on high-risk APOE4/4 individuals

That may be true, but we also know that about 100 years of research show that structured lifestyle interventions lead to short-term weight loss but almost always long-term weight regain and so I am much more interested in 4-year outcomes in the STEP Trial participants and remain curious as to why they are choosing to follow and publicize this (cardiovascular trial) population instead