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[6] Degradation [edit source] Once secreted, GLP-1 is extremely susceptible to the catalytic activity of the proteolytic enzyme dipeptidyl peptidase-4 (DPP-4)
Peptides can provide targeted effects with fewer systemic side effects but frequently still lack randomized large trials
Additionally, GLP-1R activation enhances cardiac function post- myocardial infarction, even in obese models, supporting its cardioprotective and reparative potential [98]
What happens if compounded semaglutide gets too hot
However, the optimal dosage for weight loss is yet to be determined as the medication is still under clinical trials for weight management
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