Future: Dedicated NASH Phase 3 Trial Expected Timeline IF Retatrutide Approved for Obesity/Diabetes (2028): 2027-2028: Dedicated NASH Phase 3 trial begins Population: Biopsy-confirmed NASH with fibrosis (F1-F3) Primary endpoint: NASH resolution without worsening fibrosis Baseline and Week 72-96 liver biopsies Duration: 18-24 months minimum 2029-2030: Trial results published 2030-2031: FDA approval decision for NASH indication Why This Matters Current Reality: Only one FDA-approved medication exists for NASH resmetirom (Rezdiffra), approved March 2024
After dissolving, the solution should be clear , without turbidity or floating particles
At least until 2027, those options still come from the same two companies that have already been providing these medications, Novo Nordisk and Elil Lilly
The approval could test how generics compete with branded peptide drugs in Canada, where pricing is often far below brand-name medicines
That said, it is still a good idea to keep an eye on your pet after each dose and check with your veterinarian if you notice anything unusual, even though adverse reactions are considered very rare