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doi: 10.3389/fcimb.2024.1426340 Received 01 May 2024 Accepted 29 May 2024 Published 13 August 2024 Volume 14 - 2024 Edited by Rongrong Ma, Ningbo University, China Reviewed by Jianfei Lu, Ningbo University, China Yongxiang Yu, Chinese Academy of Fishery Sciences (CAFS), China Hui Xue, Freshwater Fisheries Research Institute of Jiangsu Province, China Updates Copyright 2024 Su, Gao, Shu, Cai, Fang, Lei, Li and Hu
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In septic mice, semaglutide attenuated sickness behavior, hypothermia, systemic inflammation, and lung injury through the downregulation of pro-inflammatory cytokines (TNF- , IL-1, IL-6, CXCL1), suppression of neutrophil infiltration, and decreased expression of genes associated with tissue remodeling and inflammation (Mmp9, Timp1, Ly6g)
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