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Sleep apnea The SURMOUNT-OSA trial demonstrated that tirzepatide reduced the severity of obstructive sleep apnea significantly, with some patients achieving complete resolution
Some community members are running this sequence deliberately: start with NAD+ precursors (NMN/NR) to raise the baseline pool, then add MOTS-C to put that pool to work, then layer in 5-Amino-1MQ to block the pathway that drains it
While these symptoms are generally mild and manageable, they can impact the overall treatment experience
But if B12 is low, correcting it before or alongside those treatments removes a bottleneck that could be undermining their effectiveness
This can lead to improved texture, reduced inflammation, and a healthy glow thats hard to achieve with topical treatments alone
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