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Structure of R152H GPX4 is modeled based on PDB structure 6HN3
This genetic insight helps PlexusDx match patients to the most effective compound and dosing strategy, potentially eliminating the need for combination therapy altogether
We explored this further by depleting cells of both -arrestin isoforms to better represent the loss of recruitment of both -arrestins seen with exendin-phe1
EC, PAES, MCO, and CCPSJ have no conflicts of interest to declare
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