zepbound is the same as tirzepatide (Tirzepatide): A Q&A on Mounjaro-Like Weight Loss Drug New Zepbound Weight-Loss Drug Vials

I think first you need to know your skintype, concern and skintest them

Ochoa, Mona Sharifi, Amanda E

Thyroid-Related Concerns : Although primarily observed in rodent studies, tirzepatide carries a boxed warning regarding thyroid C-cell tumors

The findings established Ipamorelin's defining characteristic: Growth hormone Ipamorelin produced dose-dependent GH release comparable to GHRP-6 Cortisol No significant cortisol elevation was observed with Ipamorelin, while GHRP-2 and GHRP-6 produced measurable cortisol increases Prolactin No significant prolactin elevation at GH-effective concentrations ACTH No significant ACTH stimulation, contrasting with the adrenocorticotropic effects of other GHRPs GHRP Selectivity Comparison (Preclinical Data) Compound GH Release Cortisol Effect Prolactin Effect ACTH Effect Ipamorelin Dose-dependent Minimal / none Minimal / none Minimal / none GHRP-2 Dose-dependent Moderate increase Moderate increase Moderate increase GHRP-6 Dose-dependent Moderate increase Moderate increase Moderate increase Hexarelin Strong Significant increase Significant increase Significant increase Data adapted from Raun et al

The published Phase 3 mean weight reduction for retatrutide (28.3%) is nearly double the figure reported for semaglutide in STEP-1 (14.9%) over comparable trial durations [1][2][9]