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Injectable forms tend to have a higher bioavailability and a more rapid onset of action compared to oral forms, which may be subject to variations in absorption due to gastrointestinal factors

2020;33(4):e13790

Clinical Trial Evidence: Blood Pressure Outcomes Across GLP-1 Classes Multiple randomized controlled trials have quantified blood pressure changes with GLP-1 medications, revealing patterns that can inform realistic expectations

These findings suggest potential neuroprotective benefits of semaglutide, especially regarding cognitive health, and call for further research to validate its use in treating cognitive deficits and substance misuse in patients with T2DM (87)

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