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Phase II randomized study of Plitidepsin (Aplidin), alone or in association with L-carnitine, in patients with unresectable advanced renal cell carcinoma

Sitagliptin blocks DPP-4, an enzyme that breaks down incretin hormones

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If people experience nausea while taking GLP-1 injections it may be due to: Delayed Gastric Emptying: Similar to bariatric surgeries, GLP-1 medications slow down the rate at which food leaves the stomach

Such dominance of a few large-scale trials may constrain the external validity of pooled estimates and obscure underlying heterogeneity across smaller studies