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Phase 2 Metabolic Benefits Beyond weight loss, retatrutide improved cardiometabolic markers: Blood pressure: Systolic BP decreased 7.4 mmHg (12mg dose) Triglycerides: Reduced 27% from baseline Fasting glucose: Decreased 13.8 mg/dL HbA1c: Reduced 0.4% (in participants without diabetes) TRIUMPH-4: First Phase 3 Results (December 2025) TRIUMPH-4 was the first Phase 3 trial to report

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Kanoe Namahoe, 54, was diagnosed with type 2 diabetes in January and has high blood pressure

There is currently no licensed route through which retatrutide can be prescribed or obtained in the UK outside of a clinical trial

doi: 10.1007/s11938-020-00276-0