DOI: Published online: May 1, 2025 1 Department of Medicine, Seoul National University College of Medicine, Seoul, Korea 2 Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea 3 Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, Korea 4 Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, Korea 5 Wide River Institute of Immunology, Seoul National University, Hongcheon, Korea 6 Department of Brain and Cognitive Sciences, Seoul National University, Seoul, Korea Corresponding author: Hyung Jin Choi Department of Medicine, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul 03080, Korea E-mail: [email protected] Copyright 2025 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

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Es as como a medida que progresa la historia natural de la enfermedad, incluso desde la prediabetes, se pierden los efectos insulinotrpicos de esta hormona, lo que es responsable en parte de la hiperglucemia y la disfuncin de la CBP al no poder cumplir el efecto incretina, considerndose una marca distintiva de la enfermedad 49
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When an interstate closes, traffic can technically use back roads to reach the same destinations, but these roads werent designed for heavy traffic